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Michelle Alber's avatar

Great explanation Dr Marik. Thank you for your dedicated work, and for upholding professional integrity. It is outrageous how the medical establishment has persecuted good doctors, and continued to try and shut down debate, and progress with safer and more efficacious cancer treatment. It is outrageous that mainstream oncology is content to leave patients without treatment options, and leads patients to believe there are no treatment options, and to let patients die, whilst ignoring re-purposed medications that could make a real difference. Thank you for speaking out, for being a force for change, and for offering cancer patients, their families and advocates hope for the future.

Cancer & Metabolic Healing's avatar

Thanks for your support. Paul

Maybe's avatar

Thank you Dr. Marik. My only concern is that ivermectin increases my penis length and girth. So I cannot use it on a regular basis, because therr’s just so much fabric to let out in my trousers.

Cancer & Metabolic Healing's avatar

That’s cool. Another happy customer. It appears that it has not been reported in the literature. I believe you.

Cancer & Metabolic Healing's avatar

Wow.. Not heard of this before.

Mary Makary's avatar

My clitoris doubled in size, and for the first time in my life I can orgasm without direct clitoral stimulation! And I’ve only been taking ivermectin for 3 weeks.

I thought it was just me. But after reading this, I'm worried that continuous use might leave me genitally sensitized to the wind.

Cancer & Metabolic Healing's avatar

Mary. Is this a good or bad thing.

Mary Makary's avatar

It's great!👍

Only problem is Im worried if I use it long-term for prevention I might get to where I orgasm if I dare to wear pants instead of a skirt. I might have to go “trad wife.”

Cancer & Metabolic Healing's avatar

No. There are no clinical reports or recognized pharmacologic mechanisms indicating that ivermectin causes enlargement of the penis or clitoris in humans.

Human data

Regulatory safety information and post‑marketing surveillance for ivermectin list gastrointestinal, neurologic, and dermatologic adverse effects, but not genital enlargement or clitoromegaly.

The U.S. FDA has explicitly commented on concerns about reproductive toxicity and does not list genital enlargement as a known adverse effect.

Experimental and reproductive findings

Animal studies evaluating ivermectin’s reproductive effects in males have shown reduced testosterone, impaired spermatogenesis, and altered fertility parameters at certain doses, not hypertrophy of genitalia or increased erectile capacity.

One experimental study reported decreased testosterone and central neurotransmitter levels without effects on sexual motivation or penile erection.

Clitoromegaly context

Clitoromegaly is typically associated with androgen excess (e.g., PCOS, anabolic steroids, adrenal tumors, exogenous testosterone), not with antiparasitic agents such as ivermectin.

Practical takeaway

Based on current clinical experience and published data, ivermectin is not reported to cause enlargement of the penis or clitoris; if such a change occurs, alternative endocrine, pharmacologic, or structural causes should be investigated.

Cancer & Metabolic Healing's avatar

Mary. I have not heard of this happening before. Pleaase keep me updated; It may be temporary. Paul

Cancer & Metabolic Healing's avatar

No. There are no clinical reports or recognized pharmacologic mechanisms indicating that ivermectin causes enlargement of the penis or clitoris in humans.

Human data

Regulatory safety information and post‑marketing surveillance for ivermectin list gastrointestinal, neurologic, and dermatologic adverse effects, but not genital enlargement or clitoromegaly.

The U.S. FDA has explicitly commented on concerns about reproductive toxicity and does not list genital enlargement as a known adverse effect.

Experimental and reproductive findings

Animal studies evaluating ivermectin’s reproductive effects in males have shown reduced testosterone, impaired spermatogenesis, and altered fertility parameters at certain doses, not hypertrophy of genitalia or increased erectile capacity.

One experimental study reported decreased testosterone and central neurotransmitter levels without effects on sexual motivation or penile erection.

Clitoromegaly context

Clitoromegaly is typically associated with androgen excess (e.g., PCOS, anabolic steroids, adrenal tumors, exogenous testosterone), not with antiparasitic agents such as ivermectin.

Practical takeaway

Based on current clinical experience and published data, ivermectin is not reported to cause enlargement of the penis or clitoris; if such a change occurs, alternative endocrine, pharmacologic, or structural causes should be investigated.

Maybe's avatar

Paste all of the “science” you want. I know what's going on with my privates, which completely coincided with using ivermectin - And I couldn't be more thrilled about it.

larry's avatar

REALLY tell us more / dosage and such

larry's avatar

like to know why mine lost an inch erect or not after turning 65

The Cancer Strategist's avatar

It’s good to see a deeper dive into the role of ivermectin.

Even in remission, I’ve kept this repurposed drug in combination with others as part of my approach to try to control circulating tumor cells.

larry's avatar

too complicated for us stupid peole just tell us what works and dosage / dont need to build a watch just tell what timer it is :)..no disrespect intended :)

Informed Consent Freedom's avatar

Ivermectin increases my manhood tumescence. My wife says she thinks that it’s at least an inch longer.

larry's avatar

REALLY /? what is dosege and amouint please / ever since i turned 65 i have lost an inch whether erect or not

Informed Consent Freedom's avatar

4-mg daily - what do you mean amount?

larry's avatar

every day or a few days and rest

Informed Consent Freedom's avatar

That was ten days but I ran out of it.

Emily's avatar

Thank you ,you are so thorough FINALLY,a deeper understanding of this miraculous product. I know it works as i have been using it for myself as part of a homeade protocol for myself and my dog who has tumors. I like to use it on the side with chlorine dioxide and nicotine patches,the 3 are like a super power treatment.

Toni Weisskopf's avatar

What kind of tumors on your dog, if you don't mind me asking? Mine has an osteo sarcoma, and vet has not been helpful.

Emily's avatar

Not sure, I dont do vets unless I have too, but it was growing for the last year or so and I just started tackling it with my homeade lab lol. I try holistic medicine ,to many bad trips at the doctor.

Toni Weisskopf's avatar

Makes sense. Thanks for responding.

DušaTvoja's avatar

Amazing, thank you!

GeoffPainPhD's avatar

Hello Paul, long time since we met in Melbourne.

More about Mebendazole

https://geoffpain.substack.com/p/38-dropout-rate-in-hypothesis-generating

Godis Good's avatar

WOW! This is truly a phenomenally detailed article/essay of very complex mechanisms on IVMs interactions whereby cancer can be antagonized. I wonder if Dr.Marik considered putting together an educational series (audiovisual [ ? 20 minute length-bitesize duration per session?] or publication format) for science-minded & lay audiences ( or variety of series programs)to learn/review/collect the exceedingly informative,valuable, insightful, interesting and inspiring material!

Dr.Marik's brilliant contributions in the field of medicine/science/biology etc. are too invaluable to be confined only to the ranks of biomedical literacy....so many lay folks could benefit too!

Nevertheless thank you Dr.Marik for sharing your amazing understanding and brilliantly analytic intellect which is so inspiring and hopeful for many of your readers in the treatment toolbox against humanity's scourge of cancer. Your work and publications are appreciated beyond words!

Cancer & Metabolic Healing's avatar

Thanks for the very kind comments.

Robin Rosenberg's avatar

Dr. Marik,

Thank you for this extremely insightful article about the mechanisms of ivermectin as a “network-level” amplifier. During the Covid era, some enlightened physicians suggested taking ivermectin as a preventative. Considering that ivermectin has an extremely strong safety profile, do you have any thoughts on incorporating ivermectin as a preventative protocol to possibly avoid cancer?

Cancer & Metabolic Healing's avatar

I have a post on the ROOTS protocol for cancer prevention. We include ivermectin in the most aggressive protocol.

Brandon is not your bro's avatar

Thank for explaining all the mechanisms of action, very much appreciated.🤗👏🏻

John Day MD's avatar

Thank You, Dr.Marik. I will work this into the blog post I am now composing.

Bobby Blythe's avatar

Thank you for this excellent explanation of the usefulness of IVM in fighting cancer, and how it is far more effective when used in combination with other drugs.

Camille's avatar

Thank you for this great article. My sister is being treated for stage 3 or 4 ovarian cancer. While they were waiting for drs to schedule them, they began ivermectin and menbendazole amongst other alternative therapies. They met with a functional dr who did an extensive and very expensive blood panel. It revealed that ivermectin was not effective at all against the type of cancer she has. She began othe dr recommended alternative therapy. It wasn't giving her relief but we don't believe she progressed as rapidly as she could have without. She began chemo and has had remarkable results. Combined alternative w standard care. However, ivermectin was not in the protocols. Does ivermectin work in the same way described in the article for all cancers? Thank you in advance.

Cancer & Metabolic Healing's avatar

I dont believe that there is a test that shows invermectin does not work. I think the expensive tests you had done were nonsense. See my latest post on ivermectin.

Camille's avatar

Dr Marik, this is the blood test. Onconomics Plus (RGCC)

It said ivermectin was not effective in treating her cancer. It is a real test. I am surprised you don't know about it.

Cancer & Metabolic Healing's avatar

Yes, I know about this test. I am not convinced.

Camille's avatar

Do you think this test is helpful? My sister was able to continue the alternative recommended supplements and off label meds while receiving chemo. She amd her husband believe it made all the difference in how well she tolerated the chemo and it's efficacy. She has peritoneal ovarian cancer. Her markers went from over 2000 to at the moment 150. I am uncertain what the protocol is going forward. I am fairly certain they will continue alternative repurposed supplements and meds. Thanks for all you do in bringing this to the forefront. You are a blessing.

Cancer & Metabolic Healing's avatar

I would continue to do what you are doing.. seems to be working.

Kalle Pihlajasaari's avatar

Very interesting observations and synthesis. I have a question that is somewhat relevant. I accept that the human/animal biology is fashioned by the crucible of time or the benevolent hand of God. You describe a mechanism that allows ‘mutant’ or at least ‘unwanted’ cells to proliferate with innovative ‘coping skills’. My question is what purpose does this gamut of ‘coping skills’ serve in evolution/creation? Is it a hangover of a past function, a wild card in case of unimaginable novel threat or simply emergent behaviour? The more we learn the more it seems as if cancer has been baked in and I am super curious to hear what purpose it might have been intended to serve.

Cancer & Metabolic Healing's avatar

You ask a good question, I dont have a good answer.

Kalle Pihlajasaari's avatar

I just had a Twilight Zone thought pop up. What if cancer was a mechanism to create new organs that did not exist before as a test drive? Imagine if during a time of existential stress in a population numerous cancers develop and one of them somehow provides a survival benefit. Is there any genetic or epigenetic way that this might be transferred to progeny? Is there hint of a whisper of this having happened before? What is the etymology of the organs in the body, have they been created out of whole cloth or were they evolved from a 'random mutation’. The platypus lays eggs, has a bill, secretes milk and excretes a reptilian venom. Was the platypus a sandbox for testing new genes? Then how did the genes or concepts shift around the evolutionary tree?

TheFrontPorchMedia's avatar

Wow. This is the kind of science-for-dummies that I like.

Conclusion: Cancer research is complete corruption is this is not known/implemented immediately. (yeah right).