I have provided an approach to pancreatic cancer in the post entitled "Approach to repurposed drugs......" In addition you need to review the posts on dietary interventions in cancer and most importantly the post on the Metabolic trap and the 2 posts on preventing resistance. I plan on a separate post on pancreatic cancer in the future. Paul
Dr. Marik, I appreciate all that you do! I’ve been following you since the inception of the FLCCC, and I recently attended your lecture at the Everything Breast Cancer course with Lindsey Berkson and David Brownstein and it was wondrerful. My work is very focused in breast cancer and according to various papers, it seems that up to 75% of breast tumors will already have micrometastases prior to surgery. Assuming that is true, would it be best then to start this protocol at the moment of diagnosis (or sooner before a first biopsy is done), and continue through surgery (lumpectomy or mastectomy).
Thank you. I did change the word ‘paper’ to ‘study’ before I turned in last night, my time. The study has important historical value in my opinion - and yes, it is long, so I hope to hear from you again next month. Oz Dave
I think i am taking the propranolol all wrong. I am trying to do the metabolic trap. I weigh 125 lbs and am taking only 10 mg at night. Ever since chemo, 2 years ago, my resting heartbeat was usually over 100, but blood pressure has been good since losing 50 pounds. Now, with the 10 mg of propranolol before bed, blood pressure is as low as 99/55 at night (like about 2 am when getting up to go to the bathroom. ) By noon it is usually in the normal range, 120's over 80's Heart rate is 70's to 90's. I don't think I can take more as my blood pressure gets too low and I get terribly dizzy. It took me a month to titrate up to 10 mg, starting at 2.5.
Can you please recommend the dosing for pancreatic cancer. My husband is at Duke now being evaluated for the Whipple procedure. And which Root protocol should we be doing?
I take about 1000 mg of mebendazole along with ivermectin metformin, another repurpose Drugs. And an attempt to understand the cycling of doxycycline every other month with mebendazole could you please refer me to the dose of doxycycline? It would be very appreciated and helpful thank you I already have a prescription for it. I just need to understand this application.
Thank you. I assume that is still including the ivermectin, Metformin, sulfurphrane And other repurpose drugs without any concern about contraindications? Thank you for all you do. It’s been very helpful.
The most frustrating part is knowing about the various cellular pathways and treatments …. but when it’s not “standard of care “ … the lawyers come a running . Dr. Nass touched on it in your CHD interview . Sometimes I feel like I’ve wasted almost 40 years .
This article is SO very important; your strong statement at the end will hopefully be a wake up call for many clinicians. When I was operating, it sure as heck would have gotten my attention !!
Not that we know, but radiotherapy does cause cancer stem cells to proliferate. So patients receiving radiotherapy should be receiving repurposed drugs and nutraceuticals that kill stem cells.
Also, Vitamin D has been widely used to prevent metastatic cancer for over a decade
https://vitamindwiki.com/pages/metastatic-cancer-probably-reduced-by-vitamin-d-many-studies/
Strangely, in 2024 : https://vitamindwiki.com/pages/vitamin-d-is-dr-mariks-top-repurposed-drug-for-cancer-treatment/
I have provided an approach to pancreatic cancer in the post entitled "Approach to repurposed drugs......" In addition you need to review the posts on dietary interventions in cancer and most importantly the post on the Metabolic trap and the 2 posts on preventing resistance. I plan on a separate post on pancreatic cancer in the future. Paul
Dr. Marik, I appreciate all that you do! I’ve been following you since the inception of the FLCCC, and I recently attended your lecture at the Everything Breast Cancer course with Lindsey Berkson and David Brownstein and it was wondrerful. My work is very focused in breast cancer and according to various papers, it seems that up to 75% of breast tumors will already have micrometastases prior to surgery. Assuming that is true, would it be best then to start this protocol at the moment of diagnosis (or sooner before a first biopsy is done), and continue through surgery (lumpectomy or mastectomy).
I would start the Metabolic trap protocol at first diagnosis and add the periopertive meds at the time of surgery.
Thank you! Makes perfect sense!
Thank you, Dr Marik. You might be interested in this 1915 study titled “The Mortality From Cancer Throughout The World”:
https://ia801302.us.archive.org/20/items/mortalityfromcan00hoffrich/mortalityfromcan00hoffrich.pdf?utm_source=substack&utm_medium=email
Wow. Quite an extensive review.
Yes indeed. I’m tempted to purchase the book: https://www.thriftbooks.com/w/the-mortality-from-cancer-throghout-the-world/35398871/?srsltid=AfmBOoq5kdHbIIy190YN94dlFfaQpEK7zlUpDSog81mNEDfGh0JNJ2ag#edition=9808349&idiq=14787235
Thanks
A paper? 854 pages? Wow! Do you have some takeaways from this massive paper?
Thank you. I did change the word ‘paper’ to ‘study’ before I turned in last night, my time. The study has important historical value in my opinion - and yes, it is long, so I hope to hear from you again next month. Oz Dave
I think i am taking the propranolol all wrong. I am trying to do the metabolic trap. I weigh 125 lbs and am taking only 10 mg at night. Ever since chemo, 2 years ago, my resting heartbeat was usually over 100, but blood pressure has been good since losing 50 pounds. Now, with the 10 mg of propranolol before bed, blood pressure is as low as 99/55 at night (like about 2 am when getting up to go to the bathroom. ) By noon it is usually in the normal range, 120's over 80's Heart rate is 70's to 90's. I don't think I can take more as my blood pressure gets too low and I get terribly dizzy. It took me a month to titrate up to 10 mg, starting at 2.5.
Okay Try take 5mg.. if still dizzy then stop
Many thanks again, Dr. Marik. This sounds promising.
Can you please recommend the dosing for pancreatic cancer. My husband is at Duke now being evaluated for the Whipple procedure. And which Root protocol should we be doing?
I take about 1000 mg of mebendazole along with ivermectin metformin, another repurpose Drugs. And an attempt to understand the cycling of doxycycline every other month with mebendazole could you please refer me to the dose of doxycycline? It would be very appreciated and helpful thank you I already have a prescription for it. I just need to understand this application.
The dose of doxycycline is 100mg daily
Thank you. I assume that is still including the ivermectin, Metformin, sulfurphrane And other repurpose drugs without any concern about contraindications? Thank you for all you do. It’s been very helpful.
Yes, no contraindications or drug interactions.
The most frustrating part is knowing about the various cellular pathways and treatments …. but when it’s not “standard of care “ … the lawyers come a running . Dr. Nass touched on it in your CHD interview . Sometimes I feel like I’ve wasted almost 40 years .
Is vitamin k2 not helpful? I think Japanese did a study with 45 mg of K2-mk4 for breast cancer.
Yes, with Vitamin D.
Thank you for this!!! Your explanations are easy to understand for those (like myself) lacking a science-minded brain. You are a HERO!
Thank You.
What about radiotherapy, is it permetting cancer cells to spread also?
This article is SO very important; your strong statement at the end will hopefully be a wake up call for many clinicians. When I was operating, it sure as heck would have gotten my attention !!
Thank you!
Thanks. Its an important topic.
Thank You again, Dr. Marik. I’ll include this in my next blog post.
Thanks..
Thank you very much Dr. Marik
What about radiotherapy, is it permetting cancer cells to spread also?
Not that we know, but radiotherapy does cause cancer stem cells to proliferate. So patients receiving radiotherapy should be receiving repurposed drugs and nutraceuticals that kill stem cells.
Are they the same drugs that you are talking about? Thank you for this precious information!